◂ Last issue Next issue ▸ Archive   

Volume 22 (4); 2025

Research Papers

Graphic abstract

Long sleep duration and good sleep quality reduced incident peptic ulcer disease in a large Taiwanese population follow-up study
Yi-Hsiang Huang, Hsin-Yi Huang, Jia-In Lee, Ting-Yi Wu, Shu-Pin Huang, Jiun-Hung Geng, Chao-Hung Kuo, Szu-Chia Chen
Int. J. Med. Sci. 2025; 22(4): 754-763. doi:10.7150/ijms.103639
Full text PDF PubMed PMC

Graphic abstract

Metabolic dysfunction-associated fatty liver disease as a mediator of urolithiasis risk: evidence from cross-sectional and genetic studies
Lin-Tao Miao, Wen-Jie Wang, Jin-Zhou Xu, Ming-Liang Zhong, Yuan Gong, Cong Li, Yang Xun, Shao-Gang Wang
Int. J. Med. Sci. 2025; 22(4): 764-774. doi:10.7150/ijms.106824
Full text PDF PubMed PMC

Graphic abstract

Intramuscular Injection of rAAV2-retro for Low Motor Neuron Transduction: Evaluating Five Promoters
Xueqi Gong, Haitong Gao, Wenyuan Wang, Tonghui Xu
Int. J. Med. Sci. 2025; 22(4): 775-789. doi:10.7150/ijms.101807
Full text PDF PubMed PMC

Graphic abstract

Potential Biomarkers and Therapeutic Targets in Hepatitis B Virus-related Acute Liver Failure: Interplay of the Ferroptosis, Autophagy and Immune Responses
Jing Zuo, Yu-Xin Tian, Qi An, Bai-Yun Wu, Jie-Ru Yang, Yu-Chen Fan
Int. J. Med. Sci. 2025; 22(4): 806-818. doi:10.7150/ijms.106360
Full text PDF PubMed PMC

Graphic abstract

Predictivity of Hepatic Steatosis Index for Gestational Hypertension and Preeclampsia: a Prospective Cohort Study
Lin Zhang, Shen Gao, Yingyi Luan, Shaofei Su, Enjie Zhang, Jianhui Liu, Shuanghua Xie, Yue Zhang, Wentao Yue, Ruixia Liu, Chenghong Yin
Int. J. Med. Sci. 2025; 22(4): 834-844. doi:10.7150/ijms.104943
Full text PDF PubMed PMC

Graphic abstract

Identifying Water-Salt Homeostasis and Inflammatory Response in Pathological Cardiac Surgery-Associated Acute Kidney Injury: NT-proBNP-related lncRNAs and miRNAs as Novel Diagnostic Biomarkers and Therapeutic Targets
Bianfang Li, Jianhui Wang, Yuchen Gao, Xiaojing Wu, Chunrong Wang, Jin Wang, Jia Liu, Yuefu Wang
Int. J. Med. Sci. 2025; 22(4): 845-855. doi:10.7150/ijms.107589
Full text PDF PubMed PMC

Graphic abstract

Extracts of Portulaca oleracea and Patrinia scabiosaefolia relieve ultraviolet B-induced skin injury in solar dermatitis mice via inhibiting IL-17/CCL2 pathway and oxidative stress
Bowei Li, Jingyuan Yang, Zhixing Wang, Mingzhu He, Xujing Chen, Yixuan Chen, Baoying Shen, Junru Chen, Chunqi Yang, Tian Li, Chengcai Lai, Yue Gao, Hong Cai
Int. J. Med. Sci. 2025; 22(4): 856-872. doi:10.7150/ijms.106289
Full text PDF PubMed PMC

Graphic abstract

Establishment of a nomogram model based on immune-related genes using machine learning for aortic dissection diagnosis and immunomodulation assessment
Yanjun Hou, Yangyang Zhao, Zhensu Shi, Yipeng Pan, Kaijia Shi, Chaoyang Zhao, Shengnan Liu, Yongkun Chen, Lini Zhao, Jizhen Wu, Guangquan Ge, Wei Jie
Int. J. Med. Sci. 2025; 22(4): 873-886. doi:10.7150/ijms.100572
Full text PDF PubMed PMC

Graphic abstract

Accuracy of Sonographic Renal Pelvic Diameter in Assessment of Renal Function among Patients with Ureteropelvic Junction Obstruction using Scintigraphy as a Gold Standard
Mahasin G. Hassan, Tasneem S.A. Elmahdi, Moudi Alotaibi, Enas Fallatah, Faten A. Nasser
Int. J. Med. Sci. 2025; 22(4): 897-902. doi:10.7150/ijms.100216
Full text PDF PubMed PMC

Graphic abstract

Deficiency of Caveolin-1 Aggravates Cardiac Infarction Injury by Disturbing the Endothelial Homeostasis
Chunlei Liu, Junwei Zhang, Bing Qi, Zhuqing Li, Qi Li, Li Wang, Chao Li, Ziwei Wang, Zhi Qi, Chengzhi Lu
Int. J. Med. Sci. 2025; 22(4): 920-932. doi:10.7150/ijms.101074
Full text PDF PubMed PMC

Graphic abstract

Pretreatment FDG PET in prognosis of locoregionally advanced nasopharyngeal carcinoma treated with intensity-modulated radiation therapy
Xiaoshuang Niu, Fen Xue, Dan Ou, Yuming Zheng, Chaosu Hu, Chunying Shen, Xiayun He
Int. J. Med. Sci. 2025; 22(4): 933-939. doi:10.7150/ijms.105995
Full text PDF PubMed PMC

Graphic abstract

NCAPH Promotes the Proliferation of Prostate Cancer Cells Via Modulating the E2F1 Mediated PI3K/AKT/mTOR Axis
Qing Shi, Jinpeng Ma, Xiang Pan, Te Liu, Kailai Chen, Meiqi Xu, Zhichong Wu, Bin Sun, Manjie Zhang, Yakun Luo
Int. J. Med. Sci. 2025; 22(4): 940-954. doi:10.7150/ijms.103444
Full text PDF PubMed PMC

Graphic abstract

S1R mediates NRF2 dependent ferroptosis of renal tubular epithelial cells to promote renal fibrosis in diabetic nephropathy
Cheng Yuan, Fengpei Chang, Qiuyuan Zhou, Feng Chen, Xueyun Gao, Ayinigaer Yusufu, Jinhu Chen, Zejin Liao, Xiaoyan Wu, Lihua Ni
Int. J. Med. Sci. 2025; 22(4): 955-970. doi:10.7150/ijms.104324
Full text PDF PubMed PMC

Graphic abstract

Kidney Injury under Diminished Pulsatile Flow Induced by V-A ECMO in Sheep
Weidong Yan, Tianlong Wang, Jiachen Qi, Luyu Bian, Shengqiang Pei, Qiaoni Zhang, Sizhe Gao, Shujie Yan, Gang Liu, Yuan Teng, Jian Wang, Chun Zhou, Qian Wang, Jing Wang, Bingyang Ji
Int. J. Med. Sci. 2025; 22(4): 971-981. doi:10.7150/ijms.103349
Full text PDF PubMed PMC

Graphic abstract

Effects of 100 IU versus 150 IU hCG supplementation on oocyte and embryo quality in patients aged ≥ 35 years: a propensity score-matched analysis
Nguyen Thi Lien Huong, Tran Thu Thuy, Phi Thi Tu Anh, Hoang Bao Long, Le Duc Thang, Vu Thi Ngoc, Le Quang Do, Nguyen Xuan Anh Duy, Bui Thi Hanh, Do Van Loi, Le Hoang
Int. J. Med. Sci. 2025; 22(4): 982-989. doi:10.7150/ijms.106965
Full text PDF PubMed PMC

Graphic abstract

LRP5 enhances glioma cell proliferation by modulating the MAPK/p53/cdc2 pathway
Ying-Yi Feng, Xin Jin, Min-Xuan Pan, Jia-Min Liao, Xian-Zhang Huang, Chun-Min Kang
Int. J. Med. Sci. 2025; 22(4): 990-1001. doi:10.7150/ijms.99920
Full text PDF PubMed PMC

Reviews

Graphic abstract

The Role of HK2 in Tumorigenesis and Development: Potential for Targeted Therapy with Natural Products
Keren He, Fangfang Tao, Yangyuxiao Lu, Mengqi Fang, Hong Huang, Yuan Zhou
Int. J. Med. Sci. 2025; 22(4): 790-805. doi:10.7150/ijms.105553
Full text PDF PubMed PMC

Graphic abstract

Exploring the Potential of Moringa oleifera in Managing Bone Loss: Insights from Preclinical Studies
Haryati Ahmad Hairi, Rusdiah Ruzanna Jusoh, Muhammad Zulfiqah Sadikan, Wan Nuraini Wan Hasan, Ahmad Nazrun Shuid
Int. J. Med. Sci. 2025; 22(4): 819-833. doi:10.7150/ijms.103241
Full text PDF PubMed PMC

Graphic abstract

Clusterin: structure, function and roles in disease
Xing Du, Zhongyao Chen, Wei Shui
Int. J. Med. Sci. 2025; 22(4): 887-896. doi:10.7150/ijms.107159
Full text PDF PubMed PMC

Graphic abstract

Understanding Genetic Screening: Harnessing Health Information to Prevent Disease Risks
Chung-Lin Lee, Chih-Kuang Chuang, Huei-Ching Chiu, Ya-Hui Chang, Yuan-Rong Tu, Yun-Ting Lo, Hsiang-Yu Lin, Shuan-Pei Lin
Int. J. Med. Sci. 2025; 22(4): 903-919. doi:10.7150/ijms.101219
Full text PDF PubMed PMC

Graphic abstract

Aberrant DNA Methylation in Esophageal Squamous Cell Carcinoma and its Clinical Implications in Systemic Chemotherapy
Zhao Li, Xi Chen, Yongkang Li, Yan Xu, Yang Zhou
Int. J. Med. Sci. 2025; 22(4): 1002-1014. doi:10.7150/ijms.109161
Full text PDF PubMed PMC

Popup Image

©2025 Ivyspring International Publisher. Terms of use