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Volume 23 (2); 2026

Research Papers

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Glycyrrhiza glabra-Based Nasal Spray as a Novel Treatment for Chronic Rhinosinusitis with Nasal Polyps: Efficacy in Symptom Reduction and Epithelial-Mesenchymal Transition Modulation
Geng-He Chang, Pey-Jium Chang, Yu-Ching Cheng, Ching-Yuan Wu, Yao-Hsu Yang, Yu-Shih Lin, Cheng-Ming Hsu, Ming-Shao Tsai, Yao-Te Tsai, Pei-Rung Yang
Int. J. Med. Sci. 2026; 23(2): 363-377. doi:10.7150/ijms.123281
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Effects of NGR1 on the Protective Efficacy and Functional Vision Profile of Retinal Photodamage
Chi-Huang Chang, Jyh-Cheng Liou, Yi-Hsien Hsieh, Shih-Liang Yang, Chi-Wu Chang, Shao-Yun Tsai, Jui-Yi Yu, Ling Lu, Ping-Hsun Wang, Bo-Yie Chen
Int. J. Med. Sci. 2026; 23(2): 378-388. doi:10.7150/ijms.122723
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Identification and Immune Landscape Analysis of Fatty Acid Metabolism-related Genes Associated with Rheumatoid Arthritis
Zhongyang Zhou, Rong Luo, Lan Shao
Int. J. Med. Sci. 2026; 23(2): 389-405. doi:10.7150/ijms.121972
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RTMS Versus Fluvoxamine in the Treatment of OCD: A Randomized Open-label Pilot Study
Yanhua Qin, Liqiang Cai, Lingling Cheng, Ludan Xiang, Xingyue Hu
Int. J. Med. Sci. 2026; 23(2): 406-411. doi:10.7150/ijms.122621
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POFUT2 Mediated Fucosylation of JUP Enhances VEGFA Expression to Promote Angiogenesis in Colorectal Cancer
Yanfeng Zou, Yian Yang, Wei Xu, Peiguo Cao, Zheng Li
Int. J. Med. Sci. 2026; 23(2): 412-427. doi:10.7150/ijms.113515
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Discovering the abnormalities and functional importance of ferroptosis-related molecules in cervical cancer
Yu Sun, Junhua Zhang, Lingyu Guo, Jiaxin Zhang, Qian Chen, Ting Zhang, Jiaqi Yang, Yuting Zhang, Qianwei Zhen, Shuqi Chi, Gaishuang Shang, Baoxia Cui, Yunlong Cui, Youming Zhang, Youzhong Zhang, Sai Han
Int. J. Med. Sci. 2026; 23(2): 443-460. doi:10.7150/ijms.107133
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Inflammatory Biomarkers are Associated with Intimal Intracranial Artery Calcification
Dren Boshnjaku, Igor Petrov, Pranvera Ibrahimi, Edmond Komoni, Driton Shabani, Fisnik Jashari
Int. J. Med. Sci. 2026; 23(2): 461-469. doi:10.7150/ijms.124210
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Biomechanical assessment of the maxillary position after Le Fort I osteotomy using rapidly biodegradable miniplates and screws: an experimental study
Shintaro Sukegawa, Rei Hanai, Fumi Nakai, Yasuhiro Nakai, Masato Saika, Minoru Miyake
Int. J. Med. Sci. 2026; 23(2): 470-477. doi:10.7150/ijms.118208
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Hyperbaric oxygen protects against periodontal bone loss by modulating inflammation and bone remodeling via RANKL/OPG expression in ligature-induced periodontitis
Kang-Wei Tu, Chien-Cheng Huang, Mao-Tsun Lin, Ko-Chi Niu, Cheng-Hsien Lin, Pi-Yu Chao, Ching-Ping Chang, Jimmy Lian Ping Mau
Int. J. Med. Sci. 2026; 23(2): 478-496. doi:10.7150/ijms.122857
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Low hyper-oxygen exposure induces p21-dependent p53-independent senescence in alveolar cells
Cheng-Han Lee, Kan-Hsuan Lin, Ming-Sheng Lee, Chao-Jen Lin, Rei-Cheng Yang, Shih-Chung Wang, Chien-Sheng Hsu, Jun-Kai Kao
Int. J. Med. Sci. 2026; 23(2): 497-509. doi:10.7150/ijms.120133
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Missense and Intronic Variants in HNF1A Affect Prostate Cancer Aggressiveness in Patients with Biochemical Recurrence
Min-Che Tung, Yung-Wei Lin, Chung-Howe Lai, Chia-Yen Lin, Lun-Ching Chang, Yu-Ching Wen, Shun-Fa Yang, Ming-Hsien Chien
Int. J. Med. Sci. 2026; 23(2): 510-519. doi:10.7150/ijms.127638
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Coffee Consumption is Associated with a High Prevalence of Headache in a Taiwanese Population Study
Pin-Rong Chen, Chih-Hsien Hung, Sun-Wung Hsieh, Chien-Hsun Li, Tzu-Chao Lin, Szu-Chia Chen, Kuo-Wei Lee
Int. J. Med. Sci. 2026; 23(2): 520-528. doi:10.7150/ijms.123794
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Neutrophil-to-lymphocyte ratio as a predictor of post-ablation recurrence in hypertensive patients with paroxysmal atrial fibrillation
Zixi Zhang, Chao Sun, Siyuan Tan, Yichao Xiao, Tao Tu, Qiuzhen Lin, Chan Liu, Shunyi Li, Chaoshuo Liu, Cancan Wang, Murong Xie, Qiming Liu
Int. J. Med. Sci. 2026; 23(2): 529-542. doi:10.7150/ijms.118572
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The Relationship Between Thyroid Function or Subclinical Hypothyroidism in Early Pregnancy and Risk of Low Birth Weight and Small for Gestational Age of the Offspring: A Multicentre Prospective Cohort Study
Juan Li, Minhui Hu, Rong Zhao, Shuanghua Xie, Shaofei Su, Enjie Zhang, Shuangying Li, Zhan Li, Jianhui Liu, Hao Xing, Ruixia Liu, Aris T. Papageorghiou, Chenghong Yin
Int. J. Med. Sci. 2026; 23(2): 566-575. doi:10.7150/ijms.121837
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A Phase I, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Intravenous UMC119-06 in Patients with Acute Ischemic Stroke
Lung Chan, Jia-Hung Chen, Chien-Tai Hong, Yu-Cheng Lin, Jui-Hung Chang, Chien-Chang Chen, Yogi Cheng-Yo Hsuan, Chaur-Jong Hu
Int. J. Med. Sci. 2026; 23(2): 576-584. doi:10.7150/ijms.124255
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Deletion of the Mouse Homolog of Human FHR1 (muFHR1) Alleviates Atherosclerosis in ApoE-/- mice
Luce Perie, Sarah M. Herr, Tomas Ghebreslassie, Sonia Wulf, Ina Löschmann, Andjela Sekulic, Abdulhadi Suwandi, Anna-Karina B. Maier, Luca Rowlin, Berit Jungnickel, Sascha Schäuble, Gianni Panagiotou, Olaf Strauß, Thorsten Wiech, Peter F. Zipfel, Svante L. H. Zipfel, Christine Skerka
Int. J. Med. Sci. 2026; 23(2): 585-599. doi:10.7150/ijms.114990
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Computational Resolution Enhancement of Mitochondria monitoring in Multiple Organs using Intravital Two-Photon Microscopy
Saeed Bohlooli Darian, Jeongmin Oh, Jun Ki Kim
Int. J. Med. Sci. 2026; 23(2): 600-610. doi:10.7150/ijms.123395
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Transcriptomic Profiling Reveals Divergent Immune Responses to AAV1 and AAV-ie in Mice Inner Ear
Dazhi Shi, Lei Han, Can Li, Guannan Geng, Luoying Jiang, Xiaoyun Chen, Fengzhao Yang, Yong Feng, Junli Luo, Yilai Shu
Int. J. Med. Sci. 2026; 23(2): 611-619. doi:10.7150/ijms.121060
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Molecular Subtyping and Prognostic Prediction in Pancreatic Cancer Based on Mitophagy-Related Genes
Yunlong Cai, Taohua Yue, Yongchen Ma, Guanyi Liu, Jixin Zhang, Long Rong
Int. J. Med. Sci. 2026; 23(2): 620-635. doi:10.7150/ijms.121350
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Acetaminophen is associated with improved survival in critically ill lung cancer patients: A propensity score-matched cohort study
Chen Chen, Weijia Zeng, Yunyi Li, Zhihui Yang, Xue He
Int. J. Med. Sci. 2026; 23(2): 636-645. doi:10.7150/ijms.122435
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Intrahepatic Lymphangiogenesis Is Associated with Early Post-Hepatectomy Liver Regeneration, in Part via IL-6/STAT3 Signaling
Shudong Xie, Xiaofei Fan, Yang Liu, Hao Li, Chen Zhou, Chen Guo, Xiongzhuo Tang, Yingzi Ming, Pengpeng Zhang
Int. J. Med. Sci. 2026; 23(2): 646-660. doi:10.7150/ijms.106849
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Risk of new-onset glaucoma in people with carpal tunnel syndrome: a global-federated, multicenter retrospective cohort study
Yu-Jung Su, Shuo-Yan Gau, Yow-Ling Shiue
Int. J. Med. Sci. 2026; 23(2): 661-669. doi:10.7150/ijms.122874
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Artificial Intelligence-Enabled Electrocardiography for Preoperatively Detecting Atrial Fibrillation and Mortality Risk in Patients with Sinus Rhythm
Chiao-Chin Lee, Chin-Sheng Lin, Wen-Yu Lin, Chiao-Hsiang Chang, Wei-Ting Liu, Dung-Jang Tsai, Cheng-Chung Cheng, Jun-Ting Liou, Wei-Shiang Lin, Tien-Ping Tsao, Chien-Sung Tsai, Yung-Tsai Lee, Chin Lin
Int. J. Med. Sci. 2026; 23(2): 684-694. doi:10.7150/ijms.123598
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AMIGO2 as a Novel Biomarker Predicting Poor Prognosis and Associated with Adhesion-Driven Metastasis in Pancreatic Adenocarcinoma
Ze-Syuan Chen, Tsung-Shun Chang, Wan-Jou Shen, Shan-Ju Liu, Chih-Yang Wang, Yung-Kuo Lee, Wen-Hsin Hsu, Wei-Jan Wang
Int. J. Med. Sci. 2026; 23(2): 695-710. doi:10.7150/ijms.121794
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Prognostic significance of dynamic changes in systemic inflammatory markers on mortality after liver transplantation: a retrospective cohort study
Eun Jung Kim, Darhae Eum, Jin Ha Park, Seongwook Kang, Jin Sun Cho
Int. J. Med. Sci. 2026; 23(2): 711-719. doi:10.7150/ijms.126883
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Laparoscopic Omental Lymph Node Flap Transfer for Lower Extremity Lymphedema: Insights into Lymphangiogenesis and Clinical Outcomes
Chakrit Eaimkijkarn, Nutthapon Kanasup, Oumyos Rattanamahattana, Peerawan Chochai, Pornthep Sirimahachaiyakul, Worapong Leethochavalit, Tanayos Suyabodha, Chamnong Chirawichada, Wuttichai Saengprakai, Amarit Tansawet, Suphakarn Techapongsatorn
Int. J. Med. Sci. 2026; 23(2): 720-729. doi:10.7150/ijms.125568
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Reviews

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Bioengineering modification and application of bacterial outer membrane vesicles
Yedu Wen, Yidi Si, Xinni Jia, Zhongyu Han, Zihe Zhou, Zhenchao Wu, JiaJia Zheng
Int. J. Med. Sci. 2026; 23(2): 428-442. doi:10.7150/ijms.116432
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The Potential Connection Between Mechanical Stress and Heart Failure with Preserved Ejection Fraction: Mechanistic Insights and Therapeutic Potential
Hong Yang, Hong Wang, Luyun Wang, Jiangang Jiang
Int. J. Med. Sci. 2026; 23(2): 543-565. doi:10.7150/ijms.118184
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Neuroprotective Mechanisms of Hyperbaric Oxygen Therapy in Cerebral Ischemia-Hypoxia Injury Following Cardiopulmonary Resuscitation
Yifan Huang, Xiaopeng Liu, Xiaozhan Yang, Sisen Zhang
Int. J. Med. Sci. 2026; 23(2): 670-683. doi:10.7150/ijms.123862
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Links between Air Pollution and Aortic Diseases: Current Evidence for Future Prevention and Treatment
Chayatorn Chansakaow, Poon Apichartpiyakul, Siriporn C Chattipakorn, Nipon Chattipakorn
Int. J. Med. Sci. 2026; 23(2): 730-740. doi:10.7150/ijms.124106
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