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Volume 23 (7); 2026

Research Papers

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CXCL14 promotes osteosarcoma cell migration and invasion by inducing epithelial-to-mesenchymal transition Chun-Han Hou, Ming-Lung Hsu, Chen-Hsuan Wang, Ju-Fang Liu, Po-Chun Chen Int. J. Med. Sci. 2026; 23(7): 2166-2180. doi:10.7150/ijms.127140 Full text PDF PubMed PMC


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Polyinosinic:polycytidylic acid causes epithelial-mesenchymal transition via BAFF expression in Beas-2B human bronchial epithelial cells Yatham Naga Satya Mani, Dae Heum Yun, Eun-Yi Moon Int. J. Med. Sci. 2026; 23(7): 2181-2196. doi:10.7150/ijms.129414 Full text PDF PubMed PMC


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Genetic Evidence for the Benefits and Risks of Glucose-Lowering Drugs on Cardiovascular-Kidney-Metabolic Syndrome: A Drug-Target Mendelian Randomization Study Jian Lu, Shuaigang Sun, Xinru Shang, Shimin Jiang, Zekai Deng, Shunwei Wang, Chenping Wei, Jiaqi Hu, Wenge Li Int. J. Med. Sci. 2026; 23(7): 2197-2208. doi:10.7150/ijms.133077 Full text PDF PubMed PMC


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Novel Insight into the Therapeutic Targets for Spinal Degenerative Diseases Gained by a Post-Genome-Wide Association Study Xuan Zhao, Qijun Wang, Chunjie Wang, Haixia Huang, Peng Wang, Wei Wang, Jie Lu, Shibao Lu Int. J. Med. Sci. 2026; 23(7): 2209-2224. doi:10.7150/ijms.127489 Full text PDF PubMed PMC


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A Hypoxia and Immune Escape-Related Gene Signature for the Diagnosis of Prostate Cancer: An Integrated Bioinformatics Study Hexia Gan, Jiana Jiang, Jiebin Yang, Feng Shen, Weihong Lu, Peng Lai, Lingyu Chen, Zhibing Xu, Jianping Zhang, Jianming Guo, Fan Chao Int. J. Med. Sci. 2026; 23(7): 2225-2251. doi:10.7150/ijms.133397 Full text PDF PubMed PMC


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The Origin and Application of Cardiomyocyte-Derived Small Extracellular Vesicles: A Systematic Review Shaojiao Liu, Yu Teng, Sha Su, Meng Wang, Lei Wang, Mingjing Zhao Int. J. Med. Sci. 2026; 23(7): 2252-2276. doi:10.7150/ijms.133199 Full text PDF PubMed PMC


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Expanding Outcomes Beyond Chronic Kidney Disease-Mineral and Bone Disorder: A Propensity Score-Matched Analysis of Parathyroidectomy versus Calcimimetics in Dialysis Patients with Secondary Hyperparathyroidism Yi-Chou Hou¹, Cai-Mei Zheng, Ko-Lin Kuo, Kuo-Wang Tsai, Joshua Wang, Cheng-Yi Wang, Ruei-Ming Chen, Kuo-Cheng Lu Int. J. Med. Sci. 2026; 23(7): 2277-2289. doi:10.7150/ijms.131653 Full text PDF PubMed PMC


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Plumbagin sensitizes leukemia cells to cisplatin by promoting oxidative stress, apoptosis, and DNA damage Yan-Ning Chen, Jai-Wei Lee, Tsu-Ming Chien, Chia-Hung Yen, Bing-Hung Chen, Hsueh-Wei Chang Int. J. Med. Sci. 2026; 23(7): 2290-2301. doi:10.7150/ijms.124444 Full text PDF PubMed PMC


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IFN-γ+ NK cells as a potential predictor of pregnancy loss in unexplained recurrent pregnancy loss Niwei Yan, Pingyin Lee, Huiying Jie, Lingli Long, Yu Fu, Canquan Zhou, Yuan Yuan Int. J. Med. Sci. 2026; 23(7): 2302-2314. doi:10.7150/ijms.121925 Full text PDF PubMed PMC


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Pulmonary Function Tests as Predictors of Successful Tracheostomy Decannulation: A 60-Day Prospective Study Chin-Chia Yang, Wen-Lin Yu, Meng-Heng Hsieh, Ching-Tzu Huang, Mei-Hsiu Chuang, Hsing-Yu Chen Int. J. Med. Sci. 2026; 23(7): 2315-2327. doi:10.7150/ijms.126157 Full text PDF PubMed PMC


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Dual Metabolic Inhibition by Berberine and Glutor Triggers AMPK/JNK-Dependent DNA Damage in Cancer Cells Meina Shi, Chengming Wei, Dayuan Zheng, Dongfan Yang, Tong Chu, Shaokui Liang, Lu Yang, Kuanyun Zhang, Yanchao Yang, Wenzhe Ma Int. J. Med. Sci. 2026; 23(7): 2355-2375. doi:10.7150/ijms.132977 Full text PDF PubMed PMC


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Increased Risk of Injury in Patients with Fabry Disease: A Nationwide Population-Based Cohort Study in Taiwan Chun-Gu Cheng, Yu-Hsuan Chen, Wu-Chien Chien, Hung-Wen Chiu, Fei-Hung Hung, Hung-Pin Peng, Chi-Hsiang Chung, Chun-An Cheng Int. J. Med. Sci. 2026; 23(7): 2376-2386. doi:10.7150/ijms.120352 Full text PDF PubMed PMC


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Examining the influence of scarcity, weather, and vacation on physicians' performance, mortality, and costs Óscar Gasulla, Antonio Sarría-Santamera, Ferran A Mazaira-Font, Cielo García-Montero, Oscar Fraile-Martinez, Diego Cantalapiedra, Manuel F Carrillo-Rodríguez, Belen Gómez-Valcárcel, Miguel Á Ortega, Melchor Álvarez-Mon, Angel Asúnsolo Int. J. Med. Sci. 2026; 23(7): 2387-2391. doi:10.7150/ijms.124438 Full text PDF PubMed PMC


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Zingiber officinale Leaf Subcritical Water Extract Suppresses Adipogenesis and Lipogenesis in 3T3-L1 Adipocytes via the AMPK-SREBP-1c Signaling Pathway Eun-Min Jun, Jong-Yeon Kim, Jeong-Sook Choe, Eun-Jung Park, Hae-Jeung Lee Int. J. Med. Sci. 2026; 23(7): 2408-2422. doi:10.7150/ijms.121198 Full text PDF PubMed PMC


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Prognostic Role of Gut Microbiota and Clinical Parameters in Predicting Survival in Advanced Cholangiocarcinoma Patients Receiving Chemotherapy Thanika Ketpueak, Chanon Kunasol, Kanokphong Suparan, Nakarin Inmutto, Sunhawit Junrungsee, Nattayaporn Apaijai, Sasiwan Kerdphoo, Chanisa Thonusin, Chaiyut Charoentum, Thatthan Suksombooncharoen, Sarawut Kongkarnka, Sirinart Kumfu, Lakkhana Sadaow, Wanchai Maleewong, Siriporn C. Chattipakorn, Nipon Chattipakorn Int. J. Med. Sci. 2026; 23(7): 2448-2461. doi:10.7150/ijms.131376 Full text PDF PubMed PMC


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Lutein Attenuates Synovial Hyperplasia, Cartilage Loss, and Bone Erosion by Suppressing Inflammatory Pathways in Rheumatoid Arthritis Chi-Jen Chang, Tsung-Ming Chang, Ying-Sui Sun, Ji-Fan Lin, Skye Hsin-Hsien Yeh, Ju-Fang Liu Int. J. Med. Sci. 2026; 23(7): 2486-2498. doi:10.7150/ijms.135369 Full text PDF PubMed PMC

Reviews

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Biological Applications of Functionalized Cerium Oxide Nanoparticles Siyu Chen, Yuqi Gong, Fagang Jiang, Xinghua Wang Int. J. Med. Sci. 2026; 23(7): 2328-2354. doi:10.7150/ijms.134122 Full text PDF PubMed PMC


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Lactate and Lactylation in Pulmonary Hypertension: Comprehensive Landscape and Future Perspectives Qing Dai, Yichao Cai, Xinyu Wang, Xia Li, Runxiu Zheng, Xianya Cao, Chao Zhang, Jun Xu, Jian Yi, Lan Song, Aiguo Dai Int. J. Med. Sci. 2026; 23(7): 2392-2407. doi:10.7150/ijms.125397 Full text PDF PubMed PMC


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The interplay between type 2 diabetes mellitus and sepsis: a scoping review Sarah Sharul Sham, Sok Kuan Wong, Kok-Yong Chin, Nur Liyana Mohammed Yusof, Toh Leong Tan, Evelyn Yi Wen Chau, Aireen Zamhot, Amirudin Sanip, Amir Muharram Int. J. Med. Sci. 2026; 23(7): 2423-2447. doi:10.7150/ijms.126520 Full text PDF PubMed PMC


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Overcoming Biological Barriers: A Comprehensive Review of Advanced Melatonin Delivery Systems for Therapeutic Applications Zhenyu Yang, Yiduo Chen, Shaoying Li, Xiaoyue Lei, Xincheng Wu, Yuan Wang, Shuli Deng Int. J. Med. Sci. 2026; 23(7): 2462-2485. doi:10.7150/ijms.134841 Full text PDF PubMed PMC

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