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Volume 23 (3); 2026
Research Papers
LAP2 Isoform Profile in Heart Ageing and in Cardiac Cell Proliferation and Differentiation: Input From CRISPR-Cas9-mediated LAP2a Knockdown in H9C2 Nathalie Vadrot, Maryline Moulin, Ana Ferreiro, Pascale Richard, Brigitte Buendia
Int. J. Med. Sci. 2026; 23(3): 741-757. doi:10.7150/ijms.114095
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Stem cells ameliorate neurotrauma-induced visual disturbances and retinal degeneration via broad normalization of β-catenin-related signaling Shu-Chun Kuo, Chung-Hsin Tseng, Suan Hwang, Chia-Yi Lee, Ting-Feng Wu, Pi-Yu Chao, Anthony Lu, Ching-Ping Chang, Chung-Ching Chio
Int. J. Med. Sci. 2026; 23(3): 758-779. doi:10.7150/ijms.123975
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Biopsy-Proven Pulmonary Tumors Detected by LDCT: A 10-Year Single-Center Study of Growth Patterns and Diagnostic Pitfalls Chia-Tsung Hung, Chou-Chin Lan, Po-Chun Hsieh, Kun-Eng Lim, Tsung-Han Hsieh, I-Shiang Tzeng, Chih-Wei Wu
Int. J. Med. Sci. 2026; 23(3): 780-787. doi:10.7150/ijms.123625
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Integrative Evidence on Sesame Supplementation for Cardiometabolic Risk Factors Relevant to Retinopathy Wu-Hsien Kuo, Ko-Shih Chang, Fu-Hsuan Kuo, Kuan-Po Cheng, Ru-Yin Tsai
Int. J. Med. Sci. 2026; 23(3): 788-803. doi:10.7150/ijms.123717
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Efficacy of Combined Hericium erinaceus Mycelium and Undenatured Type II Collagen in Reducing Osteoarthritis Progression in a Preclinical Animal Model Kun-Tsan Lee, Chin-Jung Hsu, Li-Chai Chen, Li-Ya Lee, Wan-Ping Chen, Yu-Wen Chen, Chin-Chu Chen, Yen-You Lin, Tzu-Ching Chang, Chen-Ming Su, Chih-Hsin Tang
Int. J. Med. Sci. 2026; 23(3): 815-823. doi:10.7150/ijms.126220
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A prognostic 19-gene signature and LBP-mediated immune dysregulation define the tumor microenvironment in poor-prognosis KIRC Chia-Hung Chen, Hsiao-Hsuan Huang, Tzu-Han Weng, Ta-Wei Kuo, Nien-Che Ho, Kai-Yao Huang, Hui-Ju Kao, Chen-Lin Yu, Shun-Long Weng, Kuang-Wen Liao
Int. J. Med. Sci. 2026; 23(3): 824-842. doi:10.7150/ijms.125505
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Effect of Virtual Reality-Based Mindfulness Program vs Audio-Guided Mindfulness on Depression, Sleep, and Quality of Life in Dementia Family Caregivers: An Exploratory Randomized Controlled Trial Dorothy Bai, Yu-Hua Wang, Yu-Fang Lin, Megan F. Liu
Int. J. Med. Sci. 2026; 23(3): 843-851. doi:10.7150/ijms.126415
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Sex-Specific Prediction Models of Alzheimer's Disease: A Gene Expression Analysis Xiaomeng Ma, Abdilahi Abdi Ibrahim, Lili Ma, Xueying Ma, Zhan Ma, Yingying Liu, Donghong Li, Jia Liu, Xiaofeng Xu, Huimin Dong, Xiaohong Chen, Fuhua Peng
Int. J. Med. Sci. 2026; 23(3): 852-863. doi:10.7150/ijms.122666
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Evaluation of the Impact of Cordyceps cicadae Mycelium on Vision Health: A Cohort Study Lee Sun, Jui-Hsia Hsu, Yuan-Yen Chang, Chieh-Lin Wu, Min-Yen Hsu, Yu-Chien Hung, Chin-Chu Chen, Hui-Wen Lin
Int. J. Med. Sci. 2026; 23(3): 864-875. doi:10.7150/ijms.127003
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Melatonin inhibits FAK signaling to suppress PD-L1 expression and enhance chemosensitivity in triple-negative breast cancer Cheng-Che Wu, Ping-Fu Yang, Shu-Jyuan Chang, Mei-Ren Pan, Chung-Liang Li, Chun-Chieh Wu, Jung-Yu Kan, Fang-Ming Chen, Ming-Feng Hou, Chi-Wen Luo
Int. J. Med. Sci. 2026; 23(3): 876-888. doi:10.7150/ijms.127669
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Integrin αvβ3 is a Potential Therapeutic Target in Cholangiocarcinoma Fitria Sari Wulandari, Chih-Yang Wang, Dana R Crawford, Yung-Ning Yang, Chee-Kin Then, Sachin Kumar, Fat-Moon Suk, Lin-Yi Huang, Yu-Chen SH Yang, Zi-Lin Li, Ya-Jung Shih, Hoai Tran Tu, Kuan Wang, Hoang Dang Phu, Chun-Mao Lin, Do Thi Minh Xuan, Dahlak Daniel Solomon, Hung-Yun Lin, Jacqueline Whang-Peng
Int. J. Med. Sci. 2026; 23(3): 889-915. doi:10.7150/ijms.125066
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The role of p38 MAPK in acteoside-mediated gastric ulcer protection Yng-Tay Chen, Yun-Ju Lin, Cheng-Hsiang Tsai, Yu-Ching Lu
Int. J. Med. Sci. 2026; 23(3): 916-926. doi:10.7150/ijms.128817
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Identification of Key Genes via Integrated Multi-Omics and Machine Learning Uncovers Tumor Biological Features and Prognostic Biomarkers in Uterine Leiomyosarcoma Wei Lu, Susu Jiang, Qiran Sun, Yating Huang, Ying Yang, Xiaoqin Wang, Liwen Zhang, Yi Guo, Rujun Chen
Int. J. Med. Sci. 2026; 23(3): 927-949. doi:10.7150/ijms.126491
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Gut Microbiota Signatures and Potential Mediators in the Trajectory of Age-related Macular Degeneration: A Phased Atlas by Genetic Inference Yifan Zhou, Zhenyu Wang, Chen Huang, Xiaotong Yu, Junfu Chen, Xinhao Jiang, Jialong Dong, Qing Peng, Long Li, Xudong Song, Xinmin Lu
Int. J. Med. Sci. 2026; 23(3): 950-962. doi:10.7150/ijms.119158
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Pennisetum purpureum Schumach Supplementation Enhances Grip Strength in Adults with Low Muscle Mass: A Randomized Controlled Trial Shih-Wei Huang, Ben-Mao Liu, Yu-Hao Lee, Megan F. Liu, Eisuke Ochi, Chii-Horng Wei, Ming-Ta Yang
Int. J. Med. Sci. 2026; 23(3): 963-971. doi:10.7150/ijms.124224
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Integrative analysis of the PSMA family identifies PSMA6 as an adverse prognostic biomarker promoting bladder cancer cell proliferation Zhengnan Huang, Xiangqian Cao, Yilin Yan, Huaxing Li, Bing Shen, Tengjiao Wang
Int. J. Med. Sci. 2026; 23(3): 986-1001. doi:10.7150/ijms.119034
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An Exploratory Randomized Controlled Trial of 0.9% Saline Versus Lactated Ringer's Solution on Intraoperative Metabolism Among Patients Undergoing Lumbar Spinal Surgery Fon-Yih Tsuang, Yi-Luen Wu, Kuang-Cheng Chan, Chen-Tse Lee, Chun-Yu Wu
Int. J. Med. Sci. 2026; 23(3): 1002-1014. doi:10.7150/ijms.128640
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Machine Learning for Lymph Node Metastasis Prediction in Early Gastric Cancer: A Comparative Analysis Yufan Chen, Kunhao Bai, Minghui Yang, Chao Ma, Xiaohang Gao, Guoliang Xu, Yingbo Chen, Rong Zhang
Int. J. Med. Sci. 2026; 23(3): 1033-1045. doi:10.7150/ijms.124229
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Effects of Swimming at Different Water Temperatures on Muscle and Adipose Tissue Adaptation in Diet-Induced Obese Mice Tzu-Jung Chou, Chia-Wen Lu, Yi-Ju Hsu, Chi-Chang Huang, Kuo-Chin Huang
Int. J. Med. Sci. 2026; 23(3): 1046-1057. doi:10.7150/ijms.121250
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Effect of Bifidobacterium longum on cognition and microbiota in post-stroke patients: a single-blinded, controlled trial Shu-Ting Lin, Te-Hsuan Tung, Yen-Nung Lin, Feng-Hang Chang, Yu Zhi Lian, Chien-Hung Lai, Tsan-Hon Liou, Chi-Chang Huang, Ya-Ling Chen, Jane C.-J. Chao
Int. J. Med. Sci. 2026; 23(3): 1058-1069. doi:10.7150/ijms.124024
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Comparative Efficacy of Phacoemulsification Combined with KDB Goniotomy versus Trabeculectomy for Primary Angle-Closure Glaucoma: A Retrospective Cohort Study Xu Hou, Jing Wu, Xiaxia Yang, Jian Zhou, Dan Hu
Int. J. Med. Sci. 2026; 23(3): 1070-1079. doi:10.7150/ijms.125193
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Narciclasine triggers apoptosis in osteosarcoma cells via JNK-mediated extrinsic and intrinsic pathways Jia-Sin Yang, Chia-Hsuan Chou, Pei-Ni Chen, Yi-Hsien Hsieh, Chih-Hsin Tang, Shun-Fa Yang, Ko-Hsiu Lu
Int. J. Med. Sci. 2026; 23(3): 1080-1091. doi:10.7150/ijms.128971
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Artemisia argyi-enhanced Mesenchymal Stem Cell Exosomes Alleviates Inflammation in C28/I2 Chondrocytes by inhibiting NF-κB Shih-Wen Kao, Yu-Ting Hsu, Wei-Wen Kuo, Tai-Lung Huang, Kuan-Ho Lin, Chia-Hua Kuo, Dennis Jine-Yuan Hsieh, Tsung-Jung Ho, Shinn-Zong Lin, Chih-Yang Huang
Int. J. Med. Sci. 2026; 23(3): 1092-1104. doi:10.7150/ijms.126119
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Visnagin Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Reducing Ferroptosis Sheng-Wen Wu, Chen-Yu Chiang, Chien-Ying Lee, Shiuan-Shinn Lee, Wen-Ying Chen, Chun-Jung Chen, Ching-Chi Tseng, Yin-Che Lu, Yu-Hsiang Kuan
Int. J. Med. Sci. 2026; 23(3): 1105-1120. doi:10.7150/ijms.125642
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Low-Intensity Extracorporeal Shock Wave Therapy Alleviates Detrusor Muscle Apoptosis and Extracellular Matrix Dysregulation in the Bladder of Diabetic Rats Yau-Hsuan Tsau, Hsun-Shuan Wang, I-Hsuan Tsai, Miao-Yi Wu, Chia-Chu Liu, Tusty-Jiuan Hsieh, Yung-Chin Lee
Int. J. Med. Sci. 2026; 23(3): 1161-1173. doi:10.7150/ijms.121078
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Reviews
Role of the RBMS Family in Different Cancers and Research Progress Hanchi Wu, Rui Hou, Yuhan Zhang, Hanfang Fan, Junying Xu, Huiyu Wang
Int. J. Med. Sci. 2026; 23(3): 804-814. doi:10.7150/ijms.118386
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Dual Role of Transcription Factors in the Development and Thermogenic Function of Brown Adipose Tissue Shuai Wang, Fuan Xie, Weihua Li, Wenlong Xie, Hongqiu Cheng
Int. J. Med. Sci. 2026; 23(3): 972-985. doi:10.7150/ijms.127214
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Gene Mutations and Related Molecular Events in Distant Metastasis of Cervical Cancer: A Review Yinghua Guo, Shilong Li, Tingting Liu, Xiaolong Chang, Peiyan Qin, Nan Wang, Yingxiao Jiang, Na Lv, Niannian Li, Furong Hao
Int. J. Med. Sci. 2026; 23(3): 1015-1032. doi:10.7150/ijms.123727
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Reviewing the Peripheral and Central Mechanisms of Visceral Hypersensitivity in Intestinal Disorders Wenhui Tang, Jiarui Wang, Wenlei Wang, Jiamiao Xue, Yuyan Wang, Fuhao Jiang, Dimkpa Christabel Kechiyerunda, Shengli Gao, Tao Yuan, Feifei Guo
Int. J. Med. Sci. 2026; 23(3): 1121-1143. doi:10.7150/ijms.126361
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LIPUS as a potential strategy for anti-inflammation and repair: A review of the mechanisms Gaocheng Wang, Jianping Zhao, Jiaxuan Li, Zhanguo Zhang, Wanguang Zhang, Qian Chen, Jingjing Wang
Int. J. Med. Sci. 2026; 23(3): 1144-1160. doi:10.7150/ijms.124996
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