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Volume 23 (4); 2026

Research Papers

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Inhibitory effects of patchouli alcohol on hepatocellular carcinoma growth through accumulation of oxidative stress and inactivation of androgen receptor signaling
Xiao-Fan Huang, Kai-Fu Chang, Nu-Man Tsai
Int. J. Med. Sci. 2026; 23(4): 1174-1189. doi:10.7150/ijms.123787
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Fermented Clostridium butyricum GKB7 Inhibits Osteoarthritis Induced by Anterior Cruciate Ligament Transection in a Preclinical Model
Wei-Cheng Chen, Li-Chai Chen, You-Shan Tsai, Yen-Po Chen, Yen-Lien Chen, Chin-Chu Chen, Yen-You Lin, Tzu-Ching Chang, Chen-Ming Su, Chih-Hsin Tang
Int. J. Med. Sci. 2026; 23(4): 1190-1197. doi:10.7150/ijms.126850
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Integrated analysis uncovers KCMF1 genetic susceptibility and the SNRPD2 axis in renal cell carcinoma
Jiunn-Bey Pao, Yu-Mei Hsueh, Pei-Ling Chen, Tzu-Hao Huang, Chia-Yang Li, Jiun-Hung Geng, Te-Ling Lu, Chao-Yuan Huang, Shu-Pin Huang, Bo-Ying Bao
Int. J. Med. Sci. 2026; 23(4): 1198-1208. doi:10.7150/ijms.129880
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Development and Validation of Novel Senescence-TIME Biomarkers for Predicting the Prognosis and Immunotherapy Responsiveness of SKCM Patients
Shiying Fan, Shuya Lu, Zilong Wu, Xu Li, Yisong Gao, Gan Mao, Mao Cai, Tianyu Song, Zuojie Peng, Chong Li, Kaixiong Tao, Wei Li
Int. J. Med. Sci. 2026; 23(4): 1209-1224. doi:10.7150/ijms.127285
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Enhanced Scar Reduction Using Topical Application of Captopril-containing Silicone Gel in a Rabbit Model of Hypertrophic Scars
Jeeyoon Kim, Hyun-mu Jo, Jongweon Shin, Eun Young Rha
Int. J. Med. Sci. 2026; 23(4): 1234-1242. doi:10.7150/ijms.123608
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IDH1 mutation creates a dependency on fatty acid metabolism that underlies sensitivity to cuproptosis in acute myeloid leukemia cells
Xuening Zhang, Dayuan Zheng, Tong Chu, Dongfan Yang, Kuanyun Zhang, Shaokui Liang, Lu Yang, Wenzhe Ma
Int. J. Med. Sci. 2026; 23(4): 1243-1256. doi:10.7150/ijms.127886
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Association of NUCB2 genetic variants with the clinicopathological features of oral cancer
Chang-Chiang Yu, Hsueh-Ju Lu, Ming-Yu Lien, Chiao-Wen Lin, Jian-Hong Yu, Shun-Fa Yang, Chih-Hsin Tang
Int. J. Med. Sci. 2026; 23(4): 1257-1263. doi:10.7150/ijms.129479
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Expression of ubiquitin carboxyl-terminal hydrolase isozyme L1 and chromogranin A regulated via histone-modification through Rho/ERK/NFκB signaling in oxaliplatin-resistant colorectal cancer cells
Ko-Chao Lee, Kung-Chuan Cheng, Cheng-Yi Huang, Meng-Chiao Hsieh, Shui-Yi Tung, Yung-Yu Hsieh, Kam-Fai Lee, Chih-Chuan Teng, Hsing-Chun Kuo
Int. J. Med. Sci. 2026; 23(4): 1264-1277. doi:10.7150/ijms.126460
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Association of MIAT genetic variants and expression with tumor grade in oral tongue cancer
Ping-Ju Chen, Chiao-Wen Lin, Chun-Yi Chuang, Shun-Fa Yang, Ying-Erh Chou
Int. J. Med. Sci. 2026; 23(4): 1278-1284. doi:10.7150/ijms.129445
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Non-Coding DNA-Derived Mimotopes of Aβ₄₂ as Novel Candidates for Alzheimer's Peptide Vaccine Design
Navya Raj, Shidhi P. R, Rebai Ben Ammar, Peramaiyan Rajendran, Biju Vadakkemukadyil Chellappan
Int. J. Med. Sci. 2026; 23(4): 1320-1332. doi:10.7150/ijms.127358
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Single-cell Profiling Reveals Cooperative Participation of SPP1+ Myeloid and POSTN+ Fibroblast Subsets in Inflammation and Remodeling in Thoracic Aortic Aneurysm
Yingjiao Ju, Jingyi Yao, Song Zhang, Jiangxu Wu, Jiongao Xiang, Li Min, Mingyuan Liu
Int. J. Med. Sci. 2026; 23(4): 1333-1355. doi:10.7150/ijms.124136
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Synergistic Anticancer Effects of Lenvatinib Combined with N-butylidenephthalide in Human Colorectal Cancer Cells
Cheng-Chan Yu, Sung-Ying Huang, Shu-Fang Chang, Yu-Hung Kuo, Kuan-Fu Liao, Sheng-Chun Chiu
Int. J. Med. Sci. 2026; 23(4): 1356-1368. doi:10.7150/ijms.122381
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The efferocytosis-related genes of SLC26A6, TYRO3, and PDK4 have been identified as predictors of prognosis in hepatocellular carcinoma and are associated with the immune status
Jiao-Jiao Yang, Qing Ouyang, Xin-Xin Zeng, Wen-Jian Cen, Ling Deng, Gao-Ping Song, Fang Wang, Li-Yue Sun
Int. J. Med. Sci. 2026; 23(4): 1369-1394. doi:10.7150/ijms.120781
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Key statistical recommendations for medical journals: insights from the Global Burden of Disease Study Collaborators
Michal Ordak
Int. J. Med. Sci. 2026; 23(4): 1395-1407. doi:10.7150/ijms.119771
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Reviews

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Posterior placenta accreta spectrum: unraveling distinctive clinical features and diagnostic challenges
Yating Wu, Kuifang Shen, Caihong Hu, Jianling Wei, Jingrui Huang, Chenlin Pei
Int. J. Med. Sci. 2026; 23(4): 1225-1233. doi:10.7150/ijms.127179
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CYP450 Constraints in Infants: A Multidomain Convergence Framework for Investigating Mechanistic Vulnerability
Gary S. Goldman
Int. J. Med. Sci. 2026; 23(4): 1285-1319. doi:10.7150/ijms.129127
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