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Volume 18 (14); 2021

Research Papers

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Altered intestinal microflora and barrier injury in severe acute pancreatitis can be changed by zinc
Shi-yue Su, Qin-qing Tang
Int. J. Med. Sci. 2021; 18(14): 3050-3058. doi:10.7150/ijms.45980
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Relationship between the Metabolic Associated Fatty Liver Disease and Endometrial Thickness in Postmenopausal Women: A Cross-sectional Study in China
Jia-ying Wei, Zhou Xu, Hao Li, Wen-qin Du, Bai-ling Niu, Shu Li, Shen Tian, Juan Wu, Yu-ling Chen, Xin Li, Zi-li Liu, Jun Xiao, Guo-sheng Ren, Liang Ran, Ling-quan Kong
Int. J. Med. Sci. 2021; 18(14): 3082-3089. doi:10.7150/ijms.60780
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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BRD4 inhibition promotes TRAIL-induced apoptosis by suppressing the transcriptional activity of NF-κB in NSCLC
Liu Shi, Yu Xiong, Xiaoyan Hu, Zhihao Wang, Conghua Xie
Int. J. Med. Sci. 2021; 18(14): 3090-3096. doi:10.7150/ijms.60776
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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UHRF2 promotes Hepatocellular Carcinoma Progression by Upregulating ErbB3/Ras/Raf Signaling Pathway
Jingjie Sun, Kejia Wu, Siyuan Chen, Shiming Jiang, Yong Chen, Changzhu Duan
Int. J. Med. Sci. 2021; 18(14): 3097-3105. doi:10.7150/ijms.60030
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Microbial growth and importance of flushing inside closed-type infusion devices during administration of lipid emulsion in vitro setting
Sachiko Omotani, Yasutoshi Hatsuda, Yasuhiro Katsui, Ayumi Asao, Hiroyuki Toujou, Keigo Ihara, Katsuji Tani, Michiaki Myotoku
Int. J. Med. Sci. 2021; 18(14): 3106-3111. doi:10.7150/ijms.60200
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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HRC promotes anoikis resistance and metastasis by suppressing endoplasmic reticulum stress in hepatocellular carcinoma
Suhong Xia, Jingwen Wu, Wangdong Zhou, Mingyu Zhang, Kai Zhao, Dean Tian, Jingmei Liu, Jiazhi Liao
Int. J. Med. Sci. 2021; 18(14): 3112-3124. doi:10.7150/ijms.60610
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Ferumoxytol-β-glucan Inhibits Melanoma Growth via Interacting with Dectin-1 to Polarize Macrophages into M1 Phenotype
Xinghan Liu, Yujun Xu, Yi Li, Yuchen Pan, Shuli Zhao, Yayi Hou
Int. J. Med. Sci. 2021; 18(14): 3125-3139. doi:10.7150/ijms.61525
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Multidimensional Evaluation of All-Cause Mortality Risk and Survival Analysis for Hospitalized Patients with COVID-19
Jingwen Li, Hu Luo, Gang Deng, Jinying Chang, Xiaoming Qiu, Chen Liu, Bo Qin
Int. J. Med. Sci. 2021; 18(14): 3140-3149. doi:10.7150/ijms.58889
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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PD-L1 correlated gene expression profiles and tumor infiltrating lymphocytes in pancreatic cancer
Jiajin Li, Lu Yin, Yumei Chen, Shuxian An, Yi Xiong, Gang Huang, Jianjun Liu
Int. J. Med. Sci. 2021; 18(14): 3150-3157. doi:10.7150/ijms.61771
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Temporomandibular Disorders and Oral Features in Idiopathic Inflammatory Myopathies (IIMs) Patients: An Observational Study
Vito Crincoli, Mariangela Cannavale, Angela Pia Cazzolla, Mario Dioguardi, Maria Grazia Piancino, Mariasevera Di Comite
Int. J. Med. Sci. 2021; 18(14): 3158-3170. doi:10.7150/ijms.45226
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MiR-34a-5p and miR-452-5p: The Novel Regulators of Pancreatic Endocrine Dysfunction in Diabetic Zucker Rats?
Tong Su, Jiejun Hou, Tonghua Liu, Pei Dai, LingLing Qin, Lei Ding, Yan Hu, Xiangyu Guo
Int. J. Med. Sci. 2021; 18(14): 3171-3181. doi:10.7150/ijms.62843
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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p53-dependent apoptosis is essential for the antitumor effect of paclitaxel response to DNA damage in papillary thyroid carcinoma
Wenshuang Wu, Tao Wei, ZhiHui Li, Jingqiang Zhu
Int. J. Med. Sci. 2021; 18(14): 3197-3205. doi:10.7150/ijms.61944
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Maternal vascular endothelial growth factor receptor and interleukin levels in pregnant women with twin-twin transfusion syndrome
Nguyen Duy Anh, Phan Huyen Thuong, Nguyen Thi Sim, Tran Thi Phuong Thao, Luong Thi Lan Anh, Than Thi Thu Canh, Nguyen Van Dieu, Nguyen Duy Bac, Hoang Van Tong
Int. J. Med. Sci. 2021; 18(14): 3206-3213. doi:10.7150/ijms.61014
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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15,16-dihydrotanshinone I inhibits EOMA cells proliferation by interfering in posttranscriptional processing of hypoxia-inducible factor 1
Peiwen Duan, Yingying Huang, Kai Chen, Cheng Cheng, Zhixiang Wu, Yeming Wu
Int. J. Med. Sci. 2021; 18(14): 3214-3223. doi:10.7150/ijms.60774
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MiR-508-3p promotes proliferation and inhibits apoptosis of middle ear cholesteatoma cells by targeting PTEN/PI3K/AKT pathway
Dongliang Liu, Xiulan Ma
Int. J. Med. Sci. 2021; 18(14): 3224-3235. doi:10.7150/ijms.60907
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Therapeutic Antitumor Efficacy of Cancer Stem Cell-Derived DRibble Vaccine on Colorectal Carcinoma
Changhao Fu, Geer Tian, Jinyue Duan, Kun Liu, Chen Zhang, Weiqun Yan, Yi Wang
Int. J. Med. Sci. 2021; 18(14): 3249-3260. doi:10.7150/ijms.61510
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Alendronate-induced Perturbation of the Bone Proteome and Microenvironmental Pathophysiology
Jayoung Kim, Austin Yeon, Sarah J. Parker, Muhammad Shahid, Aissatou Thiombane, Eunho Cho, Sungyong You, Hany Emam, Do-Gyoon Kim, Minjung Kim
Int. J. Med. Sci. 2021; 18(14): 3261-3270. doi:10.7150/ijms.61552
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Optimization of artificial urine formula for in vitro cellular study compared with native urine
Kanyarat Sueksakit, Visith Thongboonkerd
Int. J. Med. Sci. 2021; 18(14): 3271-3279. doi:10.7150/ijms.61720
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Association of Hepatic Steatosis Index and Fatty Liver Index with Carotid Atherosclerosis in Type 2 Diabetes
Chenxi Wang, Zhensheng Cai, Xia Deng, Haoxiang Li, Zhicong Zhao, Chang Guo, Panpan Zhang, Lian Li, Tian Gu, Ling Yang, Li Zhao, Dong Wang, Guoyue Yuan
Int. J. Med. Sci. 2021; 18(14): 3280-3289. doi:10.7150/ijms.62010
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Analysis of the Relationship between the Expression Levels of Neutrophil Gelatinase-Associated Lipocalin and Cytokine Genes in Bone Marrow
Sungchul Mun, Min-Chul Park, Chi-Hyun Cho
Int. J. Med. Sci. 2021; 18(14): 3290-3298. doi:10.7150/ijms.62425
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Inhibition of melanogenesis by Aster yomena callus pellet extract in melanoma cells and patients with skin pigmentation
Jae-In Lee, Jeong Hun Seo, Eun-Sil Ko, Sang-Min Cho, Jea-Ran Kang, Jong-Hoon Jeong, Yu Jeong Jeong, Cha Young Kim, Jeong-Dan Cha, Woo Sik Kim, Young-Bae Ryu
Int. J. Med. Sci. 2021; 18(14): 3299-3308. doi:10.7150/ijms.62530
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Severity of frailty as a significant predictor of mortality for hemodialysis patients: a prospective study in China
Wenjing Fu, Aihua Zhang, Lina Ma, Linpei Jia, Jagadish K Chhetri, Piu Chan
Int. J. Med. Sci. 2021; 18(14): 3309-3317. doi:10.7150/ijms.51569
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Hydrogen Attenuates Myocardial Injury in Rats by Regulating Oxidative Stress and NLRP3 Inflammasome Mediated Pyroptosis
Hongxiao Yang, Shuang Liu, Huijun Du, Zi Hong, Yajing Lv, Chaoqun Nie, Wei Yang, Yunan Gao
Int. J. Med. Sci. 2021; 18(14): 3318-3325. doi:10.7150/ijms.61329
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A Retrospective Study of 158 Cases on the Risk Factors for Recurrence in Ameloblastoma
Ling Bi, Dong Wei, Dongsheng Hong, Jin Wang, Kejia Qian, Huiming Wang, Huiyong Zhu
Int. J. Med. Sci. 2021; 18(14): 3326-3332. doi:10.7150/ijms.61500
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The Incidence and Effect of Cytomegalovirus Disease on Mortality in Transplant Recipients and General Population: Real-world Nationwide Cohort Data
Sang Hoon Han, Seul Gi Yoo, Kyung Do Han, Yeonju La, Da Eun Kwon, Kyoung Hwa Lee
Int. J. Med. Sci. 2021; 18(14): 3333-3341. doi:10.7150/ijms.62621
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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IFI30 expression predicts patient prognosis in breast cancer and dictates breast cancer cells proliferation via regulating autophagy
Yan Fan, Xu Wang, Yang Li
Int. J. Med. Sci. 2021; 18(14): 3342-3352. doi:10.7150/ijms.62870
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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The role and mechanisms of Microglia in Neuromyelitis Optica Spectrum Disorders
Wenqun Li, Jiaqin Liu, Wei Tan, Yedi Zhou
Int. J. Med. Sci. 2021; 18(14): 3059-3065. doi:10.7150/ijms.61153
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A review of cutting-edge therapies for hepatocellular carcinoma (HCC): Perspectives from patents
Yan Gao, Liyang Lyu, Ye Feng, Fei Li, Yuanjia Hu
Int. J. Med. Sci. 2021; 18(14): 3066-3081. doi:10.7150/ijms.59930
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Circular RNAs Interaction with MiRNAs: Emerging Roles in Breast Cancer
Liu Gong, XiaoYun Zhou, Jiping Sun
Int. J. Med. Sci. 2021; 18(14): 3182-3196. doi:10.7150/ijms.62219
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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The role of NK cells in fighting the virus infection and sepsis
Lu Ma, Qi Li, Suna Cai, Hourong Peng, Ting Huyan, Hui Yang
Int. J. Med. Sci. 2021; 18(14): 3236-3248. doi:10.7150/ijms.59898
[Abstract] [Full text] [PDF] [PubMed] [PMC]