Int J Med Sci 2011; 8(7):635-639. doi:10.7150/ijms.8.635 This issue

Case Report

Multiple Aspergillus Cerebellar Abscesses in a Middle-Aged Female: Case Report and Literature Review

Sheng Chen1, Jia-Li Pu2, Jun Yu1* ✉, Jian-Min Zhang1* ✉

1. Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
2. Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
* Jun Yu and Jian-Min Zhang contributed equally to this paper.

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Citation:
Chen S, Pu JL, Yu J, Zhang JM. Multiple Aspergillus Cerebellar Abscesses in a Middle-Aged Female: Case Report and Literature Review. Int J Med Sci 2011; 8(7):635-639. doi:10.7150/ijms.8.635. Available from https://www.medsci.org/v08p0635.htm

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Abstract

Aspergillus abscesses in the cerebellum are extremely rare, and most cases are solitary. Here, we report the first case of multiple Aspergillus cerebellar abscesses in a 46-year-old female after one mastoidectomy, two craniectomies, and extended use of antibiotics. The possible pathogenesis of this unusual event is discussed. Good outcome was achieved by treatment with a combination of neurosurgical resection and voriconazole (VRC) administration, which we suggest is a potential management plan.

Keywords: Aspergillus, Cerebellum, Voriconazole, Neurosurgical resection