Full Text | PDF

Share on tweeters Share on facebook Share on linkedin Share on googleplus

Int J Med Sci 2021; 18(9):1975-1979. doi:10.7150/ijms.53189 This issue Cite

Research Paper

Can a multidisciplinary approach slow renal progression in CKD patients?

Ampornpan Theeranut1,2, Nonglak Methakanjanasak1, Pattama Surit1, Junto Srina3, Dhavee Sirivongs5, Doangjai Adisuksodsai3, Sunee Lertsinudom4, Kittisak Sawanyawisuth5✉

1. Department of Adult Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, 40002 Thailand.
2. Research and Training Center for Enhancing Quality of Life of Working Age People, Khon Kaen University, Khon Kaen, Thailand.
3. Department of Medicine, Chumpae Hospital, Khon Kaen, 40002Thailand.
4. Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002 Thailand.
5. Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002 Thailand.

✉ Corresponding author: Kittisak Sawanyawisuth, MD, PhD, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand, Email: kittisakac.th, Tel: 66-43-363664, Fax: 66-43-348399

Citation:
Theeranut A, Methakanjanasak N, Surit P, Srina J, Sirivongs D, Adisuksodsai D, Lertsinudom S, Sawanyawisuth K. Can a multidisciplinary approach slow renal progression in CKD patients?. Int J Med Sci 2021; 18(9):1975-1979. doi:10.7150/ijms.53189. https://www.medsci.org/v18p1975.htm
Other styles

File import instruction

Abstract

Graphic abstract

Background: Several randomized controlled trials have examined the benefits of multidisciplinary CKD care on estimated glomerular filtration rate (eGFR). But, the results are inconclusive.

Purpose: This study aimed to evaluate whether or not multidisciplinary CKD care was beneficial in terms of CKD progression.

Methods: This is a randomized controlled trial and conducted at community hospital, Thailand. The inclusion criteria were patients with age of 18 years or older and diagnosed with up to stage 3b CKD based on the KDIGO guidelines. Eligible patients divided into two groups: intervention and control group. The intervention group received a type of multidisciplinary treatment, while patients in the control group received the standard treatment administered at the outpatient clinic. The primary outcome was eGFR outcomes at three months after enrollment.

Results: During the study period, there were 334 patients who met the study criteria. Eligible patients were divided into two groups: intervention (166 patients; 49.70%) and control (168 patients; 50.30%). There were three outcomes that differed significantly between the two groups at 3 months: mean difference of eGFR from baseline, proportion of patients with eGFR decline greater than 4 mL/min/1.73 m2, and difference in CKD stage from baseline. A significantly higher percentage of patients in the intervention group experienced CKD improvement by one stage (24.10% vs 5.95%), and a significantly lower percentage experienced decline by one stage (8.43% vs 35.12%) than in the control group.

Conclusion: Slower renal progression in patients with up to stage 3b CKD was shown in patients who were treated by a multidisciplinary approach.

Keywords: CKD, education, glomerular filtration rate.

Citation styles

APA
Theeranut, A., Methakanjanasak, N., Surit, P., Srina, J., Sirivongs, D., Adisuksodsai, D., Lertsinudom, S., Sawanyawisuth, K. (2021). Can a multidisciplinary approach slow renal progression in CKD patients?. International Journal of Medical Sciences, 18(9), 1975-1979. https://doi.org/10.7150/ijms.53189.

ACS
Theeranut, A.; Methakanjanasak, N.; Surit, P.; Srina, J.; Sirivongs, D.; Adisuksodsai, D.; Lertsinudom, S.; Sawanyawisuth, K. Can a multidisciplinary approach slow renal progression in CKD patients?. Int. J. Med. Sci. 2021, 18 (9), 1975-1979. DOI: 10.7150/ijms.53189.

NLM
Theeranut A, Methakanjanasak N, Surit P, Srina J, Sirivongs D, Adisuksodsai D, Lertsinudom S, Sawanyawisuth K. Can a multidisciplinary approach slow renal progression in CKD patients?. Int J Med Sci 2021; 18(9):1975-1979. doi:10.7150/ijms.53189. https://www.medsci.org/v18p1975.htm

CSE
Theeranut A, Methakanjanasak N, Surit P, Srina J, Sirivongs D, Adisuksodsai D, Lertsinudom S, Sawanyawisuth K. 2021. Can a multidisciplinary approach slow renal progression in CKD patients?. Int J Med Sci. 18(9):1975-1979.

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Popup Image

©2024 Ivyspring International Publisher. Terms of use