An N, Chen Z, Zhao P, Yin W. Extracellular Vesicles in Sepsis: Pathogenic Roles, Organ Damage, and Therapeutic Implications. Int J Med Sci 2023; 20(13):1722-1731. doi:10.7150/ijms.86832. https://www.medsci.org/v20p1722.htm
Despite significant advances in anti-infective treatment and organ function support technology in recent years, the mortality rate of sepsis remains high. In addition to the high costs of sepsis treatment, the increasing consumption of medical resources also aggravates economic pressure and social burden. Extracellular vesicles (EVs) are membrane vesicles released from different types of activated or apoptotic cells to mediate intercellular communication, which can be detected in both human and animal body fluids. A growing body of researches suggest that EVs play an important role in the pathogenesis of sepsis. In this review, we summarize the predominant roles of EVs in various pathological processes during sepsis and its related organ dysfunction.
Keywords: sepsis, extracellular vesicles, inflammation, exosomes, organ dysfunction
Citation styles
APA
An, N., Chen, Z., Zhao, P., Yin, W. (2023). Extracellular Vesicles in Sepsis: Pathogenic Roles, Organ Damage, and Therapeutic Implications. International Journal of Medical Sciences, 20(13), 1722-1731. https://doi.org/10.7150/ijms.86832.
ACS
An, N.; Chen, Z.; Zhao, P.; Yin, W. Extracellular Vesicles in Sepsis: Pathogenic Roles, Organ Damage, and Therapeutic Implications. Int. J. Med. Sci. 2023, 20 (13), 1722-1731. DOI: 10.7150/ijms.86832.
NLM
An N, Chen Z, Zhao P, Yin W. Extracellular Vesicles in Sepsis: Pathogenic Roles, Organ Damage, and Therapeutic Implications. Int J Med Sci 2023; 20(13):1722-1731. doi:10.7150/ijms.86832. https://www.medsci.org/v20p1722.htm
CSE
An N, Chen Z, Zhao P, Yin W. 2023. Extracellular Vesicles in Sepsis: Pathogenic Roles, Organ Damage, and Therapeutic Implications. Int J Med Sci. 20(13):1722-1731.
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