ISSN: 1449-1907International Journal of Medical Sciences
Global reach, higher impact
Int J Med Sci 2022; 19(13):1847-1855. doi:10.7150/ijms.76480 This issue Cite
Review
Ferroptosis: A New Promising Target for Ovarian Cancer Therapy
1. The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
2. Department of Gynecology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Citation:
Zhao H, Xu Y, Shang H. Ferroptosis: A New Promising Target for Ovarian Cancer Therapy. Int J Med Sci 2022; 19(13):1847-1855. doi:10.7150/ijms.76480. https://www.medsci.org/v19p1847.htm
Other stylesAbstract
Ferroptosis is a novel kind of regulated cell death distinct from autophagy, apoptosis, and necrosis; it is predominantly caused by the iron-dependent lipid peroxidation. According to studies, numerous conventional signaling pathways and biological processes are implicated in the process of ferroptosis. In recent years, researchers have shown that ferroptosis plays an important role in the genesis, development, and metastasis of malignancies, including ovarian cancer. Several studies have revealed that ferroptosis has synergistic effects with chemotherapy, radiotherapy, and immunotherapy in inhibiting the growth of ovarian cancer cells. This suggests that ferroptosis is important in ovarian cancer treatment and may be a new target. In this review, we summarize the features of ferroptosis, including its underlying basis and function in ovarian cancer, as well as its potential applications in the treatment of ovarian cancer.
Keywords: ferroptosis, ovarian cancer, target, therapy
Citation styles
APA
Zhao, H., Xu, Y., Shang, H. (2022). Ferroptosis: A New Promising Target for Ovarian Cancer Therapy. International Journal of Medical Sciences, 19(13), 1847-1855. https://doi.org/10.7150/ijms.76480.
ACS
Zhao, H.; Xu, Y.; Shang, H. Ferroptosis: A New Promising Target for Ovarian Cancer Therapy. Int. J. Med. Sci. 2022, 19 (13), 1847-1855. DOI: 10.7150/ijms.76480.
NLM
Zhao H, Xu Y, Shang H. Ferroptosis: A New Promising Target for Ovarian Cancer Therapy. Int J Med Sci 2022; 19(13):1847-1855. doi:10.7150/ijms.76480. https://www.medsci.org/v19p1847.htm
CSE
Zhao H, Xu Y, Shang H. 2022. Ferroptosis: A New Promising Target for Ovarian Cancer Therapy. Int J Med Sci. 19(13):1847-1855.
This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.