Int J Med Sci
2022; 19(4):659-668.
doi:10.7150/ijms.64133 This issueCite
Review
The Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRα) in Cancers
Qingshang Li, Zhijun Cao✉, Shuliang Zhao✉
Division of Gastroenterology and Hepatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University; Shanghai Institute of Digestive Disease; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology & Hepatology, Ministry of Health. 145 Middle Shandong Road, Shanghai, China.
✉ Corresponding authors: Shuliang Zhao and Zhijun Cao, Renji Hospital, No.160 Pu Jian Ave, Shanghai 200127, China. E-mail: shuliangzhaocom and caozj_renjicom.
Citation:
Li Q, Cao Z, Zhao S. The Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRα) in Cancers. Int J Med Sci 2022; 19(4):659-668. doi:10.7150/ijms.64133. https://www.medsci.org/v19p0659.htm
Glial cell line-derived neurotrophic factor family receptor alpha (GFRα) members have been widely connected to the mechanisms contributing to cell growth, differentiation, cell migration and tissue maturation. Here we review GFRα biological functions and discussed the evidence indicating whether GFRα signaling complex present novel opportunities for oncogenic intervention and treatment resistance. Thus, our work systematically reviewed the emerging role of GFRα family members in cancers, and provided novel insights for further researches.
Li, Q., Cao, Z., Zhao, S. (2022). The Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRα) in Cancers. International Journal of Medical Sciences, 19(4), 659-668. https://doi.org/10.7150/ijms.64133.
ACS
Li, Q.; Cao, Z.; Zhao, S. The Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRα) in Cancers. Int. J. Med. Sci. 2022, 19 (4), 659-668. DOI: 10.7150/ijms.64133.
NLM
Li Q, Cao Z, Zhao S. The Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRα) in Cancers. Int J Med Sci 2022; 19(4):659-668. doi:10.7150/ijms.64133. https://www.medsci.org/v19p0659.htm
CSE
Li Q, Cao Z, Zhao S. 2022. The Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRα) in Cancers. Int J Med Sci. 19(4):659-668.
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