Int J Med Sci 2021; 18(2):564-574. doi:10.7150/ijms.53098 This issue

Research Paper

Lactose-riched Mongolian mare's milk improves physical fatigue and exercise performance in mice

Yi-Ju Hsu1, Wei-Lun Jhang1, Mon-Chien Lee1, Batsuren Bat-Otgon2, Erdenechuluun Narantungalag2, Chi-Chang Huang1✉

1. Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan City 33301, Taiwan.
2. School of Physical Education, Mongolian National University of Education, Ulaanbaatar, Mongolia.

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Citation:
Hsu YJ, Jhang WL, Lee MC, Bat-Otgon B, Narantungalag E, Huang CC. Lactose-riched Mongolian mare's milk improves physical fatigue and exercise performance in mice. Int J Med Sci 2021; 18(2):564-574. doi:10.7150/ijms.53098. Available from https://www.medsci.org/v18p0564.htm

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Abstract

Fatigue may cause the efficiency of the organ in human body to decrease, which may affect the daily life and exercise performance of the general people and athletes. Mare's milk powder (MMP) is a lactose rich supplement. The research of the study is to evaluate the whether MMP has anti-fatigue effect. Forty male ICR mice were randomly divided into four group to receive vehicle or MMP by oral gavage at 0 (Vehicle), 0.27 (MMP-1X), 0.54 (MMP-2X), 1.35 (MMP-5X) g/kg/day for 14 days. The forelimb grip of the MMP-2X, and MMP-5X group were significantly higher than the vehicle group. The swim-to-exhaustion times of the MMP-1X, MMP-2X, and MMP-5X group were significantly greater than the vehicle group. Glycogen levels in liver and muscle were significantly larger in the MMP-1X, MMP-2X, and MMP-5X groups than the vehicle group. Receive MMP supplement for 14 days can promoting exercise performance and amelioration of exercise-induced fatigue.

Keywords: mare's milk powder, anti-fatigue, lactate, glycogen storage