Int J Med Sci 2011; 8(8):640-642. doi:10.7150/ijms.8.640 This issue

Case Report

Subarachnoid Hemorrhage Associated with Epidemic Hemorrhagic Fever: A Rare Case Report

Zucai Xu1*, Ping Xu1*, Xianze Lei1, Zhongxiang Xu1, Qisi Wu2, Jun Zhang1 ✉

1. Department of Neurology, Affiliated Hospital of Zunyi Medical College, Guizhou 563003, China.
2. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
* Zucai Xu and Ping Xu contribute equally to this case report.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See for full terms and conditions.
Xu Z, Xu P, Lei X, Xu Z, Wu Q, Zhang J. Subarachnoid Hemorrhage Associated with Epidemic Hemorrhagic Fever: A Rare Case Report. Int J Med Sci 2011; 8(8):640-642. doi:10.7150/ijms.8.640. Available from

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Nervous system injuries associated with epidemic hemorrhagic fever (EHF) are not rarely seen. However, cerebrovascular disease arising from EHF is rarely reported in the literature. A 50-year-old male patient suffered from subarachnoid hemorrhage (SAH). No abnormal condition was found in intracranial vascular digital subtraction angiography (DSA). But, this patient presented with positive hantavirus-IgM and IgG, with typical clinical process, which lead to the diagnosis of EHF followed by SAH. To our knowledge, SAH associated with EHF has not been previously reported. A meticulous assessment of EHF patients with a serious condition had one or more central nervous system (CNS) abnormalities, such as sudden headache, vomiting, confusion, meningismus, and convulsions, which is necessary for diagnosing and giving timely treatment to improve the prognosis.

Keywords: Subarachnoid Hemorrhage, Epidemic Hemorrhagic Fever, Nervous System Injury