Int J Med Sci 2021; 18(10):2146-2154. doi:10.7150/ijms.53270 This issue

Research Paper

Nosocomial Infection Outbreak due to SARS-COV-2 in a Hospital Unit of Particularly Vulnerable Patients

Rocío Seijo Bestilleiro1,2, Diana Martinez Señaris2, María José Pereira Rodríguez3, Rita Galeiras Vázquez4, Raquel García Rodríguez3, María Teresa García Rodriguez1, Cristina González Martín1,5✉, María Teresa Seoane Pillado1,5, Vanesa Balboa Barreiro1,5, Valentín Valdés Valiña2, Sonia Pértega Díaz1,5

1. Research group in Nursing and Health Care, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña, A Coruña, Spain.
2. Haematology and Haemotherapy Department, Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, A Coruña, Spain.
3. Preventive Medicine Department, Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, A Coruña, Spain.
4. Intensive Care Unit, Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, A Coruña, Spain.
5. Research group in Rheumatology and Health, Universidade da Coruña, A Coruña, Spain.

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Citation:
Bestilleiro RS, Señaris DM, Rodríguez MJP, Vázquez RG, Rodríguez RG, Rodriguez MTG, Martín CG, Pillado MTS, Barreiro VB, Valiña VV, Díaz SP. Nosocomial Infection Outbreak due to SARS-COV-2 in a Hospital Unit of Particularly Vulnerable Patients. Int J Med Sci 2021; 18(10):2146-2154. doi:10.7150/ijms.53270. Available from https://www.medsci.org/v18p2146.htm

File import instruction

Abstract

Graphic abstract

Objectives: To report a COVID-19 outbreak among workers and inpatients at a medical ward for especially vulnerable patients.

Methods: Descriptive study of a nosocomial COVID-19 outbreak registered in March-April 2020 at medical ward of onco-hematological patients in an Spanish hospital. Confirmed cases were hospitalized patients, healthcare and non-healthcare workers who tested positive by PCR on a nasopharyngeal swab.

Results: Twenty-two COVID-19 cases (12 workers and 10 inpatients) were laboratory-confirmed. Initial cases were a healthcare provider and a visitor who tested positive. The median patients age was 73 years (range 62-88). The main reason of admission was haematological in 8 patients and oncologic in 2. All patients followed an immunosuppressive treatment, 5/10 with high-flow oxygen nebulizations. Five patients presented a moderate/serious evolution, and 5 patients died. The mean workers age was 42.1±10.9. One healthworker required Intensive Care Unit admission, and all of them recovered completely.

Conclusions: In the hospital setting, close patients surveillance for SARS-CoV-2 is essential, especially in immunosuppressed patients. Replacing nebulizations or high-flow oxygen therapies, when other equivalent options were available, to reduce dispersion, and controlling ventilation ducts, together with hygiene measures and an active follow-up on inpatients, visitors and workers appear to be important in preventing nosocomial outbreaks.

Keywords: COVID-19, Coronavirus Infections, Disease outbreaks, Health personnel, Infectious Disesase Transmission, Patient-to-Professional, Infectious Disease Transmission, Professional-to-Patient.