Int J Med Sci 2020; 17(15):2396-2401. doi:10.7150/ijms.48705 This issue

Research Paper

Foot health-related quality of life in hemophiliacs: A case-control study

Ana María Jiménez-Cebrián1, Daniel López-López2, Ricardo Becerro-de-Bengoa-Vallejo3, Marta Elena Losa-Iglesias4, Emmanuel Navarro-Flores5, Marta San-Antolín6, César Calvo-Lobo3, Patricia Palomo-López7✉

1. Department Nursing and Podiatry, Faculty of Health Sciences, University of Málaga, c/ Arquitecto Francisco Peñalosa 3, Ampliación del Campus de Teatinos, 29071 Málaga, Spain, Instituto de Investigación Biomédica de Málaga (IBIMA)
2. Research, Health and Podiatry Group. Department of Health Sciences, Faculty of Nursing and Podiatry. Universidade da Coruña, Ferrol, Spain.
3. Facultad de Enfermería, Fisioterapia y Podología. Universidad Complutense de Madrid, Spain.
4. Faculty of Health Sciences. Universidad Rey Juan Carlos, Spain.
5. Faculty of Nursing and Podiatry, Department of Nursing. University of Valencia. Frailty Research Organizaded Group (FROG).
6. Department of Psychology, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain.
7. University Center of Plasencia. Universidad de Extremadura, Spain.

This is an open access article distributed under the terms of the Creative Commons Attribution License ( See for full terms and conditions.
Jiménez-Cebrián AM, López-López D, Becerro-de-Bengoa-Vallejo R, Losa-Iglesias ME, Navarro-Flores E, San-Antolín M, Calvo-Lobo C, Palomo-López P. Foot health-related quality of life in hemophiliacs: A case-control study. Int J Med Sci 2020; 17(15):2396-2401. doi:10.7150/ijms.48705. Available from

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Background: Haemophilia is considered as a chronic genetic disease related with alteration in coagulation mechanism which affects to health related quality of life (HQoL).

Purpose: The goal compared marks of HQoL, in haemophiliacs with respect non haemophilic subjects.

Methods: A population of 74 subjects, were recruited from association of haemophilic illness separated in haemophilic subjects (n = 37) and no haemophilic (n = 37). For subjects who suffered haemophilia were enlisted from the association of haemophilic illness after a seminar of 45 minutes to them and to their relatives about foot health. Control subjects, were recruited from their relatives who live with the patient. The marks of the Foot Health Status Questionnaire Spanish S_FHSQ sub-scales were recompiled.

Results: All S_FHSQ domains as foot pain, foot function, tootwear, general foot health, general health, physical activity and social capacity showed lower scores in the haemophilic than non-haemophilic group (P <0.01) except for vigour (P = 0.173). Regarding the rest sub-scale marks of S_FHSQ, showed no significant difference P <0.01.

Conclusion: Subjects with a haemophilia showed significant worse foot QoL in all S_FHSQ domains except vigour domain compared with non-haemophilic subjects.

Keywords: measurement/psychometrics, quality of life, chronic pain