Risk Factors for Ventilator Dependency Following Coronary Artery Bypass Grafting

Ji, Qiang; Duan, Qianglin; Wang, Xisheng; Cai, Jianzhi; Zhou, Yongxin; Feng, Jing; Mei, Yunqing

doi:10.7150/ijms.4340

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Int J Med Sci 2012; 9(4):306-310. doi:10.7150/ijms.4340 This issue Cite

Research Paper

Risk Factors for Ventilator Dependency Following Coronary Artery Bypass Grafting

Qiang Ji^1*, Qianglin Duan^2*, Xisheng Wang¹, Jianzhi Cai¹, Yongxin Zhou¹, Jing Feng^1✉, Yunqing Mei^1✉

1. Department of Thoracic Cardiovascular Surgery, Tongji Hospital of Tongji University, 389 Xincun Rd., Shanghai, 200065, P.R. China.
2. Department of Scientific Research, Tongji Hospital of Tongji University, 389 Xincun Rd., Shanghai, 200065, P.R. China.
* Contributed equally as the co-first author.

Citation:

Ji Q, Duan Q, Wang X, Cai J, Zhou Y, Feng J, Mei Y. Risk Factors for Ventilator Dependency Following Coronary Artery Bypass Grafting. Int J Med Sci 2012; 9(4):306-310. doi:10.7150/ijms.4340. https://www.medsci.org/v09p0306.htm

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Abstract

Background: Ventilator dependency following coronary artery bypass grafting (CABG) is often associated with significant morbidity and mortality. However, few reports have focused on the independent risk factors for ventilator dependency following CABG. This study aimed to evaluate the independent risk factors for ventilator dependency following coronary artery bypass grafting (CABG). Methods: The relevant pre-, intra- and post-operative data of patients without a history of chronic obstructive pulmonary disease undergoing isolated CABG from January 2003 to December 2008 in our center were retrospectively analyzed. Elapsed time between CABG and extubation of more than 48 hours was defined as postoperative ventilator dependency (PVD). Results: The incidence of PVD was 13.8% (81/588). The in-hospital mortality in the PVD group was significantly higher than that in the non-PVD group (8.6% versus 2.4%, p=0.0092). Besides the length of ICU and hospital stay, PVD correlated with negative respiratory outcomes. The independent risk factors for PVD were preoperative congestive heart failure (OR=2.456, 95%CI 1.426-6.879), preoperative hypoalbuminemia (OR=1.353, 95%CI 1.125-3.232), preoperative arterial oxygen partial pressure (PO₂) (OR=0.462, 95%CI 0.235-0.783) and postoperative anaemia (OR=1.541, 95%CI 1.231-3.783). Conclusions: Preoperative congestive heart failure, preoperative hypoalbuminemia, low preoperative PO₂ and postoperative anaemia were identified as four independent risk factors for ventilator dependency following CABG.

Keywords: Coronary artery bypass grafting, ventilator dependency, risk factor.

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APA

Ji, Q., Duan, Q., Wang, X., Cai, J., Zhou, Y., Feng, J., Mei, Y. (2012). Risk Factors for Ventilator Dependency Following Coronary Artery Bypass Grafting. International Journal of Medical Sciences, 9(4), 306-310. https://doi.org/10.7150/ijms.4340.

ACS

Ji, Q.; Duan, Q.; Wang, X.; Cai, J.; Zhou, Y.; Feng, J.; Mei, Y. Risk Factors for Ventilator Dependency Following Coronary Artery Bypass Grafting. Int. J. Med. Sci. 2012, 9 (4), 306-310. DOI: 10.7150/ijms.4340.

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CSE

Ji Q, Duan Q, Wang X, Cai J, Zhou Y, Feng J, Mei Y. 2012. Risk Factors for Ventilator Dependency Following Coronary Artery Bypass Grafting. Int J Med Sci. 9(4):306-310.

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