Int J Med Sci 2006; 3(2):79-83. doi:10.7150/ijms.3.79 This issue Cite

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Management of HCV Infection and Liver Transplantation

Thomas D. Schiano, Paul Martin

Adult Liver Transplantation, Recanati/Miller Transplantation Institute, Division of Liver Diseases, Department of Medicine, The Mount Sinai School of Medicine, New York, NY, USA

Citation:
Schiano TD, Martin P. Management of HCV Infection and Liver Transplantation. Int J Med Sci 2006; 3(2):79-83. doi:10.7150/ijms.3.79. https://www.medsci.org/v03p0079.htm
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Abstract

A major challenge facing liver transplant recipients and their physicians is recurrence of hepatitis C virus infection following otherwise technically successful liver transplantation. Recurrent infection leads to diminished graft and patient survival. Although a number or predictors of severe recurrence have been identified, no definitive strategy has been developed to prevent recurrence. Generally the tempo of hepatitis C recurrence is gauged by serial liver biopsies with the decision to intervene with antiviral therapy based on local philosophy and expertise. Treating hepatitis C in this population has a number of major challenges including diminished patient tolerance for side-effects as well as managing the patient's immunesuppression. However sustained viral responses are possible with the potential to reduce the impact of recurrent hepatitis on the graft. However recurrent hepatitis C virus infection will remain the most frequent form of recurrent disease in liver transplant programs for the foreseeable future.

Keywords: recurrent hepatitis C, liver transplantation, antiviral therapy


Citation styles

APA
Schiano, T.D., Martin, P. (2006). Management of HCV Infection and Liver Transplantation. International Journal of Medical Sciences, 3(2), 79-83. https://doi.org/10.7150/ijms.3.79.

ACS
Schiano, T.D.; Martin, P. Management of HCV Infection and Liver Transplantation. Int. J. Med. Sci. 2006, 3 (2), 79-83. DOI: 10.7150/ijms.3.79.

NLM
Schiano TD, Martin P. Management of HCV Infection and Liver Transplantation. Int J Med Sci 2006; 3(2):79-83. doi:10.7150/ijms.3.79. https://www.medsci.org/v03p0079.htm

CSE
Schiano TD, Martin P. 2006. Management of HCV Infection and Liver Transplantation. Int J Med Sci. 3(2):79-83.

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