ISSN: 1449-1907International Journal of Medical Sciences
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Int J Med Sci 2006; 3(2):69-74. doi:10.7150/ijms.3.69 This issue Cite
Review
Treatment of Chronic HCV Infection in Special Populations
1. Division of Gastroenterology and Hepatology, H.H. Chao Comprehensive Digestive Disease Center UCI Medical Center, Orange, CA, USA.
2. Mercy Hospital and Medical Center, 2525 S Michigan Ave, Chicago, Illinois, USA.
Citation:
Hoefs J, Aulakh VS. Treatment of Chronic HCV Infection in Special Populations. Int J Med Sci 2006; 3(2):69-74. doi:10.7150/ijms.3.69. https://www.medsci.org/v03p0069.htm
Other stylesAbstract
The mainstay of treatment of chronic hepatitis C is pegylated interferon combined with ribavirin and more than 50% of naïve patients will have viral cure with either 6 months (genotypes 2 and 3) or 12 months (genotypes 1,4, and 6) with the initial treatment. However, populations have been defined that respond less well to routine treatment including African Americans, immune suppressed populations, obese patients and cirrhotic patients. These types of patients are enriched in groups of patients who are non-responders to treatment. This article discusses viral kinetics that may impact treatment response, strategies to maximize treatment effectiveness in these populations and the treatment of non-responders in general. Early viral kinetics can be used to define response or non-response and these results can be used to modify subsequent treatment length and dose.
Keywords: HCV, treatment HCV, non-responder, cirrhosis, African American, fatty liver
Citation styles
APA
Hoefs, J., Aulakh, V.S. (2006). Treatment of Chronic HCV Infection in Special Populations. International Journal of Medical Sciences, 3(2), 69-74. https://doi.org/10.7150/ijms.3.69.
ACS
Hoefs, J.; Aulakh, V.S. Treatment of Chronic HCV Infection in Special Populations. Int. J. Med. Sci. 2006, 3 (2), 69-74. DOI: 10.7150/ijms.3.69.
NLM
Hoefs J, Aulakh VS. Treatment of Chronic HCV Infection in Special Populations. Int J Med Sci 2006; 3(2):69-74. doi:10.7150/ijms.3.69. https://www.medsci.org/v03p0069.htm
CSE
Hoefs J, Aulakh VS. 2006. Treatment of Chronic HCV Infection in Special Populations. Int J Med Sci. 3(2):69-74.
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