Int J Med Sci 2012; 9(1):40-46. doi:10.7150/ijms.9.40 This issue
1. Department of Obstetrics and Gynecology, College of Medicine, Catholic University of Korea.
2. Department of Psychiatry, College of Medicine, Catholic University of Korea.
3. Department of Biostatistics, College of Medicine, Catholic University of Korea.
✉ Corresponding author: Jong Chul Shin, MD. Department of Obstetrics and Gynecology, College of Medicine, Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul 137-040, Korea. E-mail: firstname.lastname@example.org; Phone: 82-2-2258-2813; Fax: 82-2-595-1549.Conflict of Interest: The authors have declared that no conflict of interest exists.
The identification of antenatal depression is critical but poorly conducted. The aim of this study was to construct a simplified depression survey scale and to verify its efficacy as a pre-screening for antenatal depression. A total of 494 pregnant women in the third trimester of gestation who had received antenatal care at Seoul St. Mary's Hospital from July 2009 to June 2010 were included. The Edinburgh Postnatal Depression Scale (EPDS) questionnaire was completed by them. The subjects were randomly divided into two groups: 250 of training set and 244 of validation set. We designed a simplified questionnaire comprising two items of EPDS using the training set. We then validated its efficacy with the training set and reaffirmed the results with the validation set. The sum of item 5 (scare or panic) and item 8 (sadness or misery) explained 75.5% of the total score of the EPDS (AUC = 0.947). Using a score of 3 as a cut-off value of the simplified scale, sensitivity was 92.4% and specificity was 86.3%. The positive and negative predictive values were 56.2% and 98.4%, retrospectively. This study suggests that the simplified EPDS can be an efficient instrument to rule out depression during pregnancy.
Keywords: Antenatal depression, Edinburgh Postnatal Depression Scale, Screening, Perinatal mental health, Depression.